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JoVE Journal Neuroscience
Beeldvorming en kwantificering van intacte neuronale dendrieten via CLARITY Tissue Clearing
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Beeldvorming en kwantificering van intacte neuronale dendrieten via CLARITY Tissue Clearing

Article DOI: 10.3791/62532-v • 07:45 min • April 20th, 2021
April 20th, 2021 •
1, 1,2, 1,2, 2, 1,3
1Department of Genetics and Genomics, Baylor College of Medicine, 2Medical Scientist Training Program, Baylor College of Medicine, 3Department of Neuroscience, Baylor College of Medicine

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Neuronale dendritische morfologie ligt vaak ten grondslag aan functie. Inderdaad, veel ziekteprocessen die de ontwikkeling van neuronen beïnvloeden, manifesteren zich met een morfologisch fenotype. Dit protocol beschrijft een eenvoudige en krachtige methode voor het analyseren van intacte dendritische priëlen en hun bijbehorende stekels.

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Neurowetenschappen Nummer 170
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