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Journal / Bioengineering / Udvikling af 3D-organiseret humant hjertevæv…
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JoVE Journal Bioengineering
Udvikling af 3D-organiseret humant hjertevæv inden for en mikrofluidisk platform
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Udvikling af 3D-organiseret humant hjertevæv inden for en mikrofluidisk platform

Article DOI: 10.3791/62539-v • 10:42 min • June 15th, 2021
June 15th, 2021 •
1, 1,2
1School of Biological and Health Systems Engineering, Arizona State University, 2Biodesign Virginia G. Piper Center for Personalized Diagnostics, Arizona State University

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Målet med denne protokol er at forklare og demonstrere udviklingen af en tredimensionel (3D) mikrofluidisk model af højt justeret humant hjertevæv, der består af stamcelle-afledte kardiomyocytter, der er co-dyrket med hjertefibroblaster (CF'er) inden for en biomimetisk, kollagenbaseret hydrogel til applikationer i hjertevævsteknik, lægemiddelscreening og sygdomsmodellering.

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Bioengineering Problem 172 stamcelle hjertevæv mikromiljø myokardie mikrofluidiske chips
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