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Reconstruir el retinoblastoma humano in vitro
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Reconstruir el retinoblastoma humano in vitro

Article DOI: 10.3791/62629-v • 06:52 min • October 11th, 2022
October 11th, 2022 •
1, 1
1Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Laboratory

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Describimos un método para generar retinoblastoma humano (RB) mediante la introducción de mutaciones bialélicas RB1 en células madre embrionarias humanas (hESC). Las líneas celulares RB también podrían cultivarse con éxito utilizando el RB aislado en una placa.

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Investigación del cáncer Número 188
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