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Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma
Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma

Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma

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07:59 min

September 03, 2021

DOI:

07:59 min
September 03, 2021

6390 Views
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Summary

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Portal vein injection of colorectal cancer (CRC) organoids generates stroma-rich liver metastasis. This mouse model of CRC hepatic metastasis represents a useful tool to study tumor-stroma interactions and develop novel stroma-directed therapeutics such as adeno-associated virus-mediated gene therapies.

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