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Cancer Research
Cancer Research
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门静脉注射结直肠癌类器官研究肝转移基质
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Article
DOI:
10.3791/62630-v
•
07:59 min
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September 3rd, 2021
门静脉注射结直肠癌类器官研究肝转移基质
September 3rd, 2021
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Hiroki Kobayashi1,2,3,4, Krystyna A. Gieniec1,2, Jia Q. Ng1,2, Jarrad Goyne1,2, Tamsin R. M. Lannagan1,2, Elaine M. Thomas1,2, Georgette Radford1,2, Tongtong Wang1,2, Nobumi Suzuki1,2,5, Mari Ichinose1,2, Josephine A. Wright2, Laura Vrbanac1,2, Alastair D. Burt6, Masahide Takahashi3,4,7, Atsushi Enomoto3, Daniel L. Worthley2, Susan L. Woods1,2
1Adelaide Medical School, University of Adelaide, 2South Australian Health and Medical Research Institute (SAHMRI), 3Department of Pathology, Nagoya University Graduate School of Medicine, 4Division of Molecular Pathology, Center for Neurological Disease and Cancer, Nagoya University Graduate School of Medicine, 5Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 6Translational and Clinical Research Institute, Newcastle University, 7International Center for Cell and Gene Therapy, Fujita Health University
Chapters
Summary
Please note that all translations are automatically generated.
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门静脉注射结直肠癌 (CRC) 类器官可产生富含基质的肝转移。这种CRC肝转移的小鼠模型代表了研究肿瘤 - 基质相互作用和开发新型基质导向疗法(如腺相关病毒介导的基因疗法)的有用工具。