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Journal / Cancer Research / 肝転移間質を研究するための結腸直腸癌オルガノイドの門脈注入…
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Cancer Research

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JoVE Journal Cancer Research
肝転移間質を研究するための結腸直腸癌オルガノイドの門脈注入
Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays
Journal (Cancer Research)
Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays
Creation and Maintenance of a Living Biobank - How We Do It
Journal (Cancer Research)
Creation and Maintenance of a Living Biobank - How We Do It
 
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肝転移間質を研究するための結腸直腸癌オルガノイドの門脈注入

Article DOI: 10.3791/62630-v • 07:59 min • September 3rd, 2021
September 3rd, 2021 •
1,2,3,4, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2,5, 1,2, 2, 1,2, 6, 3,4,7, 3, 2, 1,2
1Adelaide Medical School, University of Adelaide, 2South Australian Health and Medical Research Institute (SAHMRI), 3Department of Pathology, Nagoya University Graduate School of Medicine, 4Division of Molecular Pathology, Center for Neurological Disease and Cancer, Nagoya University Graduate School of Medicine, 5Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 6Translational and Clinical Research Institute, Newcastle University, 7International Center for Cell and Gene Therapy, Fujita Health University

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結腸直腸癌(CRC)オルガノイドの門脈注入は、間質に富む肝転移を生じる。CRC肝転移のこのマウスモデルは、腫瘍間質相互作用を研究し、アデノ随伴ウイルス媒介遺伝子治療などの新規間質指向性治療薬を開発するための有用なツールである。

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がん研究 第175号
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