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Journal / Immunology and Infection / Retrograde Ohrspeicheldrüseninfusion durch…
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Immunology and Infection
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JoVE Journal Immunology and Infection
Retrograde Ohrspeicheldrüseninfusion durch Stensen-Kanal in einem nicht-menschlichen Primaten für vektorierte Genabgabe
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Retrograde Ohrspeicheldrüseninfusion durch Stensen-Kanal in einem nicht-menschlichen Primaten für vektorierte Genabgabe

Article DOI: 10.3791/62645-v • 03:50 min • August 12th, 2021
August 12th, 2021 •
1, 2, 3, 4, 3, 3,5
1Department of Medicine, Division of Infectious Diseases and Global Medicine, University of Florida, 2Department of Otolaryngology, George Washington University School of Medicine, 3Department of Medicine, Section on Infectious Diseases, Wake Forest Baptist Medical Center, 4Department of Pathology, Wake Forest School of Medicine, 5Department of Medicine, Section of Infectious Diseases, Hefner Veterans Affairs Medical Center

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Speicheldrüsen wurden als Gewebezielstelle für die Gentherapie vorgeschlagen, insbesondere im Bereich der Impfung durch Gentransfer. Wir demonstrieren die Genabgabe in einem nicht-menschlichen Primatenmodell mit retrograder Ohrspeicheldrüseninfusion.

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Immunologie und Infektion Heft 174 Retrograde Speicheldrüseninfusion Speicheldrüse vektorierte Immunprophylaxe Impfung durch Gentransfer nichtmenschlicher Primat Ohrspeicheldrüseninfusion Gentherapie
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