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JoVE Journal Neuroscience
Evaluation der motorischen Beeinträchtigung bei C. elegans Modellen der amyotrophen Lateralsklerose
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Evaluation der motorischen Beeinträchtigung bei C. elegans Modellen der amyotrophen Lateralsklerose

Article DOI: 10.3791/62699-v • 08:27 min • September 2nd, 2021
September 2nd, 2021 •
1, 1,2
1Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, 2Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington

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Dieses Protokoll beschreibt zwei empfindliche Assays zur Unterscheidung zwischen leichter, mittelschwerer und schwerer motorischer Beeinträchtigung in C. elegans-Modellen der amyotrophen Lateralsklerose, mit allgemeinem Nutzen für C. elegans-Stämme mit veränderter Motilität.

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Neuroscience Ausgabe 175
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