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Hepatosellüler Karsinomdaki Tümör-Stromalkileşimi Araştırmak İçin Üç Boyutlu Sferoid Modeli…
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Cancer Research
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Hepatosellüler Karsinomdaki Tümör-Stromal Etkileşimi Araştırmak İçin Üç Boyutlu Sferoid Modeli
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Article
DOI:
10.3791/62868-v
•
12:24 min
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September 30th, 2021
Hepatosellüler Karsinomdaki Tümör-Stromal Etkileşimi Araştırmak İçin Üç Boyutlu Sferoid Modeli
September 30th, 2021
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Marco Y. W. Zaki*1,2, Shishir Shetty*2, Alex L. Wilkinson2, Daniel A. Patten2, Fiona Oakley*3, Helen Reeves*4,5
1Department of Biochemistry, Faculty of Pharmacy, Minia University, 2National Institute for Health Research Birmingham Liver Biomedical Research Unit and Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University of Birmingham, 3Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, 4Newcastle University Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, 5The Liver Unit, Department of Medicine, Freeman Hospital, Newcastle-upon-Tyne Hospitals NHS Foundation Trust
* These authors contributed equally
Chapters
Summary
Please note that all translations are automatically generated.
Click here for the English version.
İlgili insan hastalığını sadakatle nükseden kapsamlı in vitro modeller eksiktir. Mevcut çalışma, insan hepatosellüler karsinomunda tümör-stromal etkileşimi incelemek için güvenilir bir in vitro araç olan üç boyutlu (3D) tümör sferoid oluşturma ve kültürü ssunuyor.