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Cancer Research

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Analytisk bestemmelse av mitokondriefunksjon av utskilte faste tumor homogenater
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Analytisk bestemmelse av mitokondriefunksjon av utskilte faste tumor homogenater

Article DOI: 10.3791/62875-v • 11:32 min • August 6th, 2021
August 6th, 2021 •
1,2,3, 1, 2,4, 1,3
1Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, 2Clinical Oncology and Metabolism, Pennington Biomedical Research Center, 3Department of Nutrition, Case Western Reserve University, 4Department of Clinical Nutrition, University of Texas Southwestern Medical Center

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Vi utviklet en praktisk protokoll og analytisk tilnærming for å evaluere mitokondrie oksidativ fosforylering og elektronoverføringskapasitet i friske tumor homogenater. Denne protokollen kan enkelt tilpasses for å kartlegge ulike mitokondriefunksjoner som bidrar til kreftinitiering, progresjon og behandlingsrespons.

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Kreftforskning utgave 174
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