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Biochemistry

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JoVE Journal Biochemistry
Produktion av siRNA-laddade lipidnanopartiklar med hjälp av en mikrofluidisk enhet
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Produktion av siRNA-laddade lipidnanopartiklar med hjälp av en mikrofluidisk enhet

Article DOI: 10.3791/62999-v • 06:02 min • March 22nd, 2022
March 22nd, 2022 •
1,2, 3, 3, 3, 1, 1, 1
1Division of Applied Chemistry, Faculty of Engineering, Hokkaido University, 2JST PRESTO, 3Graduate School of Chemical Sciences and Engineering, Hokkaido University

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Mikrofluidbaserade lipidnanopartiklar (LNP) produktionsmetoder har väckt uppmärksamhet i drug delivery system (DDS), inklusive RNA-leverans. Detta protokoll beskriver tillverkning, LNP (siRNA-laddade LNP) produktion och LNP utvärderingsprocesser med hjälp av vår ursprungliga mikrofluidiska enhet som heter iLiNP.

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Biokemi nummer 181
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