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Journal / Biochemistry / Mikroakışkan Cihaz Kullanılarak siRNA Yüklü Lipid …
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Biochemistry

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JoVE Journal Biochemistry
Mikroakışkan Cihaz Kullanılarak siRNA Yüklü Lipid Nanopartiküllerinin Üretimi
Covalent Immobilization of Proteins for the Single Molecule Force Spectroscopy
Journal (Biochemistry)
Covalent Immobilization of Proteins for the Single Molecule Force Spectroscopy
Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Journal (Biochemistry)
Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
 
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Mikroakışkan Cihaz Kullanılarak siRNA Yüklü Lipid Nanopartiküllerinin Üretimi

Article DOI: 10.3791/62999-v • 06:02 min • March 22nd, 2022
March 22nd, 2022 •
1,2, 3, 3, 3, 1, 1, 1
1Division of Applied Chemistry, Faculty of Engineering, Hokkaido University, 2JST PRESTO, 3Graduate School of Chemical Sciences and Engineering, Hokkaido University

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RNA teslimatı da dahil olmak üzere ilaç dağıtım sistemlerinde (DDS) mikroakışkan bazlı lipid nanopartikül (LNP) üretim yöntemleri dikkat çekmiştir. Bu protokol, iLiNP adlı orijinal mikroakışkan cihazımızı kullanarak imalat, LNP (siRNA yüklü LNP) üretimi ve LNP değerlendirme süreçlerini açıklar.

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