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Neuroscience

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JoVE Journal Neuroscience
En musemodel af direkte anastomose via den præspinale rute til krydsning af nerveoverførselskirurgi
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En musemodel af direkte anastomose via den præspinale rute til krydsning af nerveoverførselskirurgi

Article DOI: 10.3791/63051-v • 05:56 min • October 19th, 2021
October 19th, 2021 •
*1,2, *1, *1, 1, 1, 1, 1, 1,2,3,4,5, 1,2,3,4,5
1Department of Hand Surgery, Huashan Hospital, Fudan University, 2Department of Hand and Upper Extremity Surgery, Jing‘an District Central Hospital, Fudan University, 3The National Clinical Research Center for Aging and Medicine, Fudan University, 4Institutes of Brain Science, Fudan University, 5State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center of Brain Science, Fudan University
* These authors contributed equally

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Vi simulerede klinisk kirurgi for at etablere en protokol for direkte anastomose af bilaterale brachiale plexusnerver via præspinalruten hos mus, hvilket bidrog til undersøgelsen af de neurale mekanismer, der ligger til grund for rehabilitering ved krydsning af nerveoverførsel efter skader på det centrale og perifere nervesystem.

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Denne måned i JoVE udgave 176 Prespinal rute nerveoverførselskirurgi Brachial plexus avulsionsskader reparation af øvre ekstremiteter hjerneskadebehandling funktionel genopretning neuroplasticitet perifer sensorimotorisk intervention neurale mekanismer klinisk dyremodel bilaterale brachiale plexusnerver neuroanatomiske eksperimenter elektrofysiologiske eksperimenter adfærdsmæssige eksperimenter reinnervering nedsat forben motorisk genopretning
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