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JoVE Journal Neuroscience
Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging (MRI)
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Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging (MRI)

Article DOI: 10.3791/63150-v • 06:30 min • December 16th, 2021
December 16th, 2021 •
*1, *1, 1, 1, 2,3, 2,3, 1, 1
1Department of Neurosurgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, and Humboldt-Universität zu Berlin, and Berlin Institute of Health, 2Department of Experimental Neurology and Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 3NeuroCure Cluster of Excellence and Charité Core Facility 7T Experimental MRIs, Charité - Universitätsmedizin Berlin
* These authors contributed equally

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Summary
Automatic Translation

Here we present a standardized SAH mouse model, induced by endovascular filament perforation, combined with magnetic resonance imaging (MRI) 24 h after operation to ensure the correct bleeding site and exclude other relevant intracranial pathologies.

Tags

Endovascular Perforation Model Subarachnoid Hemorrhage Magnetic Resonance Imaging Bleeding Volume Subgroup Analysis Mouse Ophthalmic Ointment Sanitization Lidocaine Supine Position Carotid Artery Sheath Surgical Field Silk Suture ECA (external Carotid Artery) ICA (internal Carotid Artery) Vessel Stump Filament Ligation
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