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JoVE Journal Bioengineering
Et mikrofysiologisk system til undersøgelse af leukocyt-endotelcelleinteraktion under betændelse
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Et mikrofysiologisk system til undersøgelse af leukocyt-endotelcelleinteraktion under betændelse

Article DOI: 10.3791/63312-v • 12:55 min • December 9th, 2021
December 9th, 2021 •
1, 2, 3, 4, 5, 1,2,6
1Department of Mechanical Engineering, Temple University, 2Department of Bioengineering, Temple University, 3Department of Bioengineering, University of Toledo, 4Biomedical Technology, CFD Research Corporation, 5Center for Inflammation and Lung Research, Department of Microbiology, Immunology and Inflammation, Lewis Katz School of Medicine, Temple University, 6Department of Radiation Oncology, Lewis Katz School of Medicine, Temple University

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I denne protokol anvendes et biomimetisk mikrofluidassay, som kan reproducere et fysiologisk relevant mikrovaskulært miljø og reproducere hele leukocytadhæsionen / migrationskaskaden, til at studere leukocyt-endotelcelleinteraktioner i inflammatorisk sygdom.

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Bioengineering udgave 178 mikrofysiologisk system leukocyt-endotelcelleinteraktion inflammation vedhæftning migration biomimetisk mikrofluidassay
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