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JoVE Journal Bioengineering
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Un système microphysiologique pour étudier l’interaction leucocytaire-endothéliale pendant l’inflammation

Article DOI: 10.3791/63312-v • 12:55 min • December 9th, 2021
December 9th, 2021 •
1, 2, 3, 4, 5, 1,2,6
1Department of Mechanical Engineering, Temple University, 2Department of Bioengineering, Temple University, 3Department of Bioengineering, University of Toledo, 4Biomedical Technology, CFD Research Corporation, 5Center for Inflammation and Lung Research, Department of Microbiology, Immunology and Inflammation, Lewis Katz School of Medicine, Temple University, 6Department of Radiation Oncology, Lewis Katz School of Medicine, Temple University

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Dans ce protocole, un test de microfluide biomimétique, qui peut reproduire un environnement microvasculaire physiologiquement pertinent et reproduire l’ensemble de la cascade d’adhésion / migration des leucocytes, est utilisé pour étudier les interactions leucocytes-cellules endothéliales dans les maladies inflammatoires.

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Bioingénierie numéro 178 système microphysiologique interaction leucocytaire-cellule endothéliale inflammation adhésion migration dosage biomimétique des microfluides
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