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07:41 min
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June 08, 2022
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Il tasso di consumo di ossigeno (OCR) è un proxy comune per la funzione mitocondriale e può essere utilizzato per studiare diversi modelli di malattia. Abbiamo sviluppato un nuovo metodo utilizzando un analizzatore Seahorse XF per misurare direttamente l'OCR in fette striatal acute di topi adulti che è più fisiologicamente rilevante rispetto ad altri metodi.
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Cite this Article
Zhi, L., Zhao, J., Jaffe, D., Chen, Y., Wang, N., Qin, Q., Seifert, E. L., Li, C., Zhang, H. Measurement of Oxygen Consumption Rate in Acute Striatal Slices from Adult Mice. J. Vis. Exp. (184), e63379, doi:10.3791/63379 (2022).
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