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JoVE Journal Cancer Research
Samlet shRNA-bibliotekscreening for å identifisere faktorer som modulerer en legemiddelresistensfenotype
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Samlet shRNA-bibliotekscreening for å identifisere faktorer som modulerer en legemiddelresistensfenotype

Article DOI: 10.3791/63383-v • 14:51 min • June 17th, 2022
June 17th, 2022 •
1,2, 1,2, 2,3, 2,3, 1,2,3, 1,2,3
1Department of Clinical Haematology, Christian Medical College, 2Department of Biotechnology, Thiruvalluvar University, 3Centre for Stem Cell Research, Christian Medical College

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RNAi-screening (High-throughput RNA interference) ved hjelp av et basseng med lentivirale shRNAer kan være et verktøy for å oppdage terapeutisk relevante syntetiske dødelige mål i maligniteter. Vi tilbyr en samlet shRNA screening tilnærming for å undersøke epigenetiske effektorer i akutt myeloid leukemi (AML).

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Kreftforskning Utgave 184 Screening med høy gjennomstrømning RNAi-screening shRNA epigenetisk faktor cytarabin AraC-resistens
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