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Journal / Neuroscience / Optroden-Array zur simultanen optogenetischen…
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JoVE Journal Neuroscience
Optroden-Array zur simultanen optogenetischen Modulation und elektrischen neuronalen Aufzeichnung
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Optroden-Array zur simultanen optogenetischen Modulation und elektrischen neuronalen Aufzeichnung

Article DOI: 10.3791/63460-v • 06:36 min • September 1st, 2022
September 1st, 2022 •
*1,2, *3, 3, 1, 1, 1,2, 3,4, 1,2,5
1Department of Electronic and Electrical Engineering, Ewha Womans University, 2Graduate Program in Smart Factory, Ewha Womans University, 3Department of Electrical and Computer Engineering, Seoul National University, 4Graduate School of Engineering Practice, Seoul National University, 5Department of Brain and Cognitive Sciences, Ewha Womans University
* These authors contributed equally

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Hier stellen wir das Herstellungsverfahren eines Optrode-Systems mit optischen Fasern für die Lichtabgabe und einem Elektrodenarray für die neuronale Aufzeichnung vor. In-vivo-Experimente mit transgenen Mäusen, die Kanalrhodopsin-2 exprimieren, zeigen die Machbarkeit des Systems für die gleichzeitige optogenetische Stimulation und elektrophysiologische Aufzeichnung.

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Neuroscience Ausgabe 187
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