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Journal / Neuroscience / Oprode Array para modulação optogenética…
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JoVE Journal Neuroscience
Oprode Array para modulação optogenética simultânea e gravação neural elétrica
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Oprode Array para modulação optogenética simultânea e gravação neural elétrica

Article DOI: 10.3791/63460-v • 06:36 min • September 1st, 2022
September 1st, 2022 •
*1,2, *3, 3, 1, 1, 1,2, 3,4, 1,2,5
1Department of Electronic and Electrical Engineering, Ewha Womans University, 2Graduate Program in Smart Factory, Ewha Womans University, 3Department of Electrical and Computer Engineering, Seoul National University, 4Graduate School of Engineering Practice, Seoul National University, 5Department of Brain and Cognitive Sciences, Ewha Womans University
* These authors contributed equally

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Aqui, apresentamos o método de fabricação de um sistema optrode com fibras ópticas para entrega de luz e uma matriz de eletrodos para gravação neural. Experimentos in vivo com camundongos transgênicos expressando channelrhodopsin-2 mostram a viabilidade do sistema para estimulação optogenética simultânea e gravação eletrofisiológica.

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Neurociência Edição 187
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