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Journal / Immunology and Infection / Darmorganoide für Hunde in einem durchlässigen…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Darmorganoide für Hunde in einem durchlässigen Zweikammer-Trägersystem
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Darmorganoide für Hunde in einem durchlässigen Zweikammer-Trägersystem

Article DOI: 10.3791/63612-v • 11:11 min • March 2nd, 2022
March 2nd, 2022 •
1, 1, 2, 3, 2, 3, 4, 5, 2, 2,3, 1,3
1Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, 2Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, 33D Health Solutions Inc., 4Office of New Animal Drug Evaluation, Center for Veterinary Medicine, Food and Drug Administration, 5Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration

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Hier stellen wir ein Protokoll vor, das die Kultur der Darmorganoide von Hunden in einem durchlässigen Zweikammer-Stützsystem beschreibt. Die organoide Aussaat in den durchlässigen Trägern, die Monolayer-Wartung und nachfolgende Wirkstoffpermeabilitätsexperimente werden beschrieben.

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Immunologie und Infektion Ausgabe 181 Durchlässige Unterstützung Doppelkammer Hund Organoid Darm Stammzelle Translationale Forschung Reverse translationale Forschung One Health Initiative Wirkstoffforschung Arzneimittelpermeabilität
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