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JoVE Journal Neuroscience
Biochemische Reinigung und proteomische Charakterisierung von Amyloid-Fibrillenkernen aus dem Gehirn
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Biochemische Reinigung und proteomische Charakterisierung von Amyloid-Fibrillenkernen aus dem Gehirn

Article DOI: 10.3791/63816-v • 09:00 min • April 28th, 2022
April 28th, 2022 •
1, 1, 1
1Department of Neurology, Northwestern University Feinberg School of Medicine

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Diese biochemische Reinigungsmethode mit massenspektrometriebasierter Proteomanalyse erleichtert die robuste Charakterisierung von Amyloidfibrillenkernen, was die Identifizierung von Zielen zur Vorbeugung der Alzheimer-Krankheit beschleunigen kann.

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Neurowissenschaften Ausgabe 182 Amyloid Alzheimer Massenspektrometrie Proteomik Proteinaggregate Proteinreinigung Strukturbiologie
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