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Journal / Bioengineering / Chip glomerulo renale isogenico ingegnerizzato da …
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JoVE Journal Bioengineering
Chip glomerulo renale isogenico ingegnerizzato da cellule staminali pluripotenti indotte umane
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Chip glomerulo renale isogenico ingegnerizzato da cellule staminali pluripotenti indotte umane

Article DOI: 10.3791/63821-v • 10:23 min • November 4th, 2022
November 4th, 2022 •
1, 1,2,3,4
1Department of Biomedical Engineering, Pratt School of Engineering, Duke University, 2Department of Medicine, Division of Nephrology, Duke University School of Medicine, 3Department of Cell Biology, Duke University, 4Center for Biomolecular and Tissue Engineering, Duke University

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Presentato qui è un protocollo per progettare un sistema organo-on-a-chip personalizzato che ricapitola la struttura e la funzione della barriera di filtrazione glomerulare renale integrando cellule endoteliali epiteliali e vascolari geneticamente abbinate differenziate dalle cellule staminali pluripotenti indotte umane. Questo sistema bioingegnerizzato può far progredire la medicina di precisione renale e le applicazioni correlate.

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Bioingegneria Numero 189
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