Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Bioengineering / Fabrication and Characterization of…
JoVE Journal
Bioengineering

A subscription to JoVE is required to view this content.

JoVE Journal Bioengineering
Fabrication and Characterization of Layer-By-Layer Janus Base Nano-Matrix to Promote Cartilage Regeneration
Sustained Administration of β-cell Mitogens to Intact Mouse Islets Ex Vivo Using Biodegradable Poly(lactic-co-glycolic acid) Microspheres
Journal (Bioengineering)
Sustained Administration of β-cell Mitogens to Intact Mouse Islets Ex Vivo Using Biodegradable Poly(lactic-co-glycolic acid) Microspheres
Development of an Electrochemical DNA Biosensor to Detect a Foodborne Pathogen
Journal (Bioengineering)
Development of an Electrochemical DNA Biosensor to Detect a Foodborne Pathogen
 

Fabrication and Characterization of Layer-By-Layer Janus Base Nano-Matrix to Promote Cartilage Regeneration

Article DOI: 10.3791/63984-v • 08:55 min • July 6th, 2022
July 6th, 2022 •
*1, *1, 1
1Department of Biomedical Engineering, University of Connecticut
* These authors contributed equally

Chapters

Summary
Automatic Translation

This protocol describes the assembly of a layer-by-layer Janus base nano-matrix (JBNm) scaffold by adding Janus base nanotubes (JBNts), matrilin-3, and Transforming Growth Factor Beta-1 (TGF-β1) sequentially. The JBNm was fabricated and characterized; additionally, it displayed excellent bioactivity, encouraging cell functions such as adhesion, proliferation, and differentiation.

Tags

Fabrication Characterization Layer-by-Layer Janus Base Nano-Matrix Cartilage Regeneration TGF-B1 Chondrogenesis Growth Factor Encapsulation Localized Release Hypertrophy Homeostatic Microenvironment Injectable Fractures Cavities Matrilin-3 JBNts
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter