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JoVE Journal Neuroscience
Härstamningsspårning av inducerbara fluorescerande märkta stamceller i den vuxna mushjärnan
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Härstamningsspårning av inducerbara fluorescerande märkta stamceller i den vuxna mushjärnan

Article DOI: 10.3791/63998-v • 09:44 min • May 20th, 2022
May 20th, 2022 •
1,2, 2, 3, 1,2
1Graduate School of Biomedical Science and Engineering, University of Maine, 2Department of Neurosurgery, Ohio State University Wexner Medical Center, 3Boston Children’s Hospital, Harvard Medical School

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Förmågan att permanent markera stamceller och deras avkomma med en fluorofor med hjälp av en inducerbar transgen härstamning som spårar muslinjen möjliggör rumslig och tidsmässig analys av aktivering, proliferation, migration och / eller differentiering in vivo. Härstamningsspårning kan avslöja ny information om härstamningsengagemang, svar på interventioner och multipotens.

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Neurovetenskap utgåva 183
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