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Intestinal Epithelial Regeneration in Response to Ionizing Irradiation
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Intestinal Epithelial Regeneration in Response to Ionizing Irradiation

Article DOI: 10.3791/64028-v • 09:10 min • July 27th, 2022
July 27th, 2022 •
1, 1, 1, 1,2, 1
1Department of Medicine, Renaissance School of Medicine at Stony Brook University, 2Department of Physiology and Biophysics, Renaissance School of Medicine at Stony Brook University

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Summary
Automatic Translation

The gastrointestinal tract is one of the most sensitive organs to injury upon radiotherapeutic cancer treatments. It is simultaneously an organ system with one of the highest regenerative capacities following such insults. The presented protocol describes an efficient method to study the regenerative capacity of the intestinal epithelium.

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Intestinal Epithelial Regeneration Ionizing Irradiation Gamma Irradiation Colorectal Cancer Treatment Gastrointestinal Tract Cell Activation Cell Differentiation Cell Migration Radiation Injury Model Intestinal Cell Fate Regenerative Capacity Lineage-tracing Animal Models Microbiota Epithelial Cell Population Stromal Cell Population Immune Cell Population Tamoxifen Powder Corn Oil EdU Powder DMSO Tissue Collection
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