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Journal / Biology / 结合3D磁力致动器和多功能荧光成像来研究细胞核力学生物学…
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结合3D磁力致动器和多功能荧光成像来研究细胞核力学生物学
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结合3D磁力致动器和多功能荧光成像来研究细胞核力学生物学

Article DOI: 10.3791/64098-v • 06:54 min • July 5th, 2022
July 5th, 2022 •
1,5, 1,5, 1, 1, 2, 3,5, 4, 5,6,7, 1, 1,5,8,9
1Department of Mechanical and Aerospace Engineering, Herbert Wertheim College of Engineering, University of Florida, 2Department of Materials Science and Engineering, University of Florida, 3Department of Biostatistics, University of Florida, 4Department of Biomedical Engineering, College of Engineering (COE), University of Delaware (UD), 5UF Health Cancer Center, University of Florida, 6Department of Physics, College of Liberal Arts and Sciences, University of Florida, 7Department of Anatomy and Cell Biology, College of Medicine, University of Florida, 8J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, 9Department of Physiology and Functional Genomics, University of Florida

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本研究提出了一种新的方案，通过传递到细胞质中的磁性微珠直接对细胞核施加机械力，并同时进行活细胞荧光成像。

Tags

生物学，第185期，原子核力学生物学，磁力，CRISPR/Cas9，机械转导，软活性物质，是相关蛋白（YAP），荧光功能成像，数字成像处理，光遗传学，表观遗传学
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