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Desestabilização do Menisco Medial e Cartilagem Scratch Murine Modelo de Osteoartrite Acelerada
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Desestabilização do Menisco Medial e Cartilagem Scratch Murine Modelo de Osteoartrite Acelerada

Article DOI: 10.3791/64159-v • 07:06 min • July 6th, 2022
July 6th, 2022 •
1, 1, 1, 2, 2
1Institute of Biomedical and Environmental Health Research, University of the West of Scotland, 2Institute of Infection, Immunity and Inflammation, University of Glasgow

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O presente protocolo descreve os arranhões controlados da microlâmina na superfície da cartilagem articular após a desestabilização do joelho do camundongo pelo corte do ligamento miniscotibial medial. Este modelo animal apresenta uma forma acelerada de osteoartrite (OA) adequada para estudar a formação de osteófitos, osteosclerose e dor em estágio inicial.

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Medicina Edição 185
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