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JoVE Journal Neuroscience
通过产 卵电 穿孔解剖听觉回路中脆性X智力迟钝蛋白的细胞自主功能
A Fully Automated and Highly Versatile System for Testing Multi-cognitive Functions and Recording Neuronal Activities in Rodents
Journal (Neuroscience)
A Fully Automated and Highly Versatile System for Testing Multi-cognitive Functions and Recording Neuronal Activities in Rodents
Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
Journal (Neuroscience)
Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
 
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通过产 卵电 穿孔解剖听觉回路中脆性X智力迟钝蛋白的细胞自主功能

Article DOI: 10.3791/64187-v • 11:10 min • July 6th, 2022
July 6th, 2022 •
*1, *2, 3, 1
1Division of Histology & Embryology, Key Laboratory for Regenerative Medicine of the Ministry of Education, College of Medicine, Jinan University, 2Department of Clinical Pathology, First Affiliated Hospital of Jinan University, 3Program in Neuroscience, Department of Biomedical Sciences, College of Medicine, Florida State University
* These authors contributed equally

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利用 卵 电穿孔，我们设计了一种选择性转染鸡胚胎中听觉内耳和耳蜗核的方法，以实现在电路组装的离散期间脆性X智力迟钝蛋白的细胞组特异性敲低。

Tags

神经科学，第185期，脆性X综合征，感觉回路，内耳，耳蜗核，突触形成，大脑发育，Held的末端球茎，鸡胚
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