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Immunology and Infection

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JoVE Journal Immunology and Infection
A Mouse Model of Orotracheal Intubation and Ventilated Lung Ischemia Reperfusion Surgery
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A Mouse Model of Orotracheal Intubation and Ventilated Lung Ischemia Reperfusion Surgery

Article DOI: 10.3791/64383-v • 09:07 min • September 9th, 2022
September 9th, 2022 •
*1, *1, 1,2, 1, 1, 1, 3, 1
1Department of Anesthesia and Perioperative Care, University of California San Francisco and San Francisco General Hospital, 2Department of Physiology, School of Medicine, Tehran University of Medical Sciences, 3Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine
* These authors contributed equally

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Summary
Automatic Translation

A mouse surgical model to create left lung ischemia reperfusion (IR) injury while maintaining ventilation and avoiding hypoxia.

Tags

Mouse Model Orotracheal Intubation Ventilated Lung Ischemia-reperfusion Surgery Lung Specific Pathophysiology Multiple Processes Lung Transplantation Pulmonary Embolism Lung Injury Hemorrhagic Trauma With Resuscitation Inflammatory Contributions Atelectasis Mechanical Ventilation Hypoxia In Vivo Circulatory Immune System Longer-term Studies Sterile Inflammation Control Microsurgical Technique Practice Hours Euthanized Mouse Cardiac Activity Distraction Blood Stasis In Left PA Fiber Optic Flexible Light Anesthetized Mouse Vocal Cords Illumination Levels Adjustment Intubation Technique
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