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JoVE Journal
Bioengineering

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颗粒稳定乳液的细胞亲和力促进抗原内化
 
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颗粒稳定乳液的细胞亲和力促进抗原内化

Article DOI: 10.3791/64406-v 10:06 min September 2nd, 2022
September 2nd, 2022

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Summary

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为了合理设计高效的佐剂,我们开发了聚乳酸-乙醇酸纳米颗粒稳定的皮克林乳液(PNPE)。PNPE具有独特的柔软性和疏水界面,可实现有效的细胞接触,并提供高含量的抗原负载,改善递送系统与抗原呈递细胞的细胞亲和力,并诱导抗原的有效内化。

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生物工程,第187期,
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