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Journal / Immunology and Infection / Phagenvermittelte genetische Manipulation der…
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Immunology and Infection

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Phagenvermittelte genetische Manipulation der Borreliose Spirochete Borrelia burgdorferi
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Phagenvermittelte genetische Manipulation der Borreliose Spirochete Borrelia burgdorferi

Article DOI: 10.3791/64408-v • 09:01 min • September 28th, 2022
September 28th, 2022 •
1
1Department of Biomedical Sciences, Quinnipiac University

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Die Fähigkeit von Bakteriophagen, DNA zwischen Bakterienzellen zu bewegen, macht sie zu wirksamen Werkzeugen für die genetische Manipulation ihrer bakteriellen Wirte. Hier wird eine Methodik zur Induktion, Wiederherstellung und Verwendung von φBB-1, einem Bakteriophagen von Borrelia burgdorferi, vorgestellt, um heterologe DNA zwischen verschiedenen Stämmen der Lyme-Borreliose Spirochäte zu transduzieren.

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Immunologie und Infektion Ausgabe 187 Borrelia burgdorferi Bakteriophagen horizontaler Gentransfer Transduktion
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