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JoVE Journal Cancer Research
Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
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Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma

Article DOI: 10.3791/64623-v • 06:08 min • June 2nd, 2023
June 2nd, 2023 •
1,3, 2, 3, 4, 3, 3, 1,3, 1,3, 2, 1,3
1Precision Medicine Research Center, Sichuan Provincial Key Laboratory of Precision Medicine, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, 2Department of Thyroid Surgery, West China Hospital, Sichuan University, 3Sichuan Kangcheng Biotech Co., 4Sichuan Cancer Hospital

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Summary
Automatic Translation

The present protocol establishes and characterizes a patient-derived xenograft (PDX) model of anaplastic thyroid carcinoma (ATC) and head and neck squamous cell carcinoma (HNSCC), as PDX models are rapidly becoming the standard in the field of translational oncology.

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Patient-derived Xenograft Models Anaplastic Thyroid Carcinoma Head And Neck Squamous Cell Carcinoma Tumor Heterogeneity Molecular Diversity Clinic Outcomes Anti-cancer Drug Sensitivity Screening Personalized Treatment ATC And HNSCC Tumor Samples HTK Solution Disinfection Ophthalmic Forceps Petri Dish Saline Cutting Tumor Tissue Sealing Film Pathogen-free Animal Room Inoculation Needles Anesthetizing The Mouse Right Lateral Thorax
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