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Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea

Article DOI: 10.3791/64691-v • 07:36 min • December 23rd, 2022
December 23rd, 2022 •
1, 1, 1, 1, 1, 1
1Chongqing Engineering Research Center of Pharmaceutical Evaluation of Chinese Medicine, Chongqing Academy of Chinese Materia Medica

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Here, a comparative analysis of raw and processed Cyperi rhizoma (CR) samples is presented using ultra-high performance liquid chromatography-high-resolution tandem mass spectrometry (UPLC-MS/MS) in rats with primary dysmenorrhea. The changes in blood levels of the metabolites and the sample constituents were examined between rats treated with CR and CR processed with vinegar (CRV).

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Raw Cyperi Rhizoma Processed Cyperi Rhizoma Liquid Chromatography-Tandem Mass Spectrometry Rats Primary Dysmenorrhea Metabonomics Traditional Chinese Medicine Active Ingredients Drug Components Screening Individual Constituents Endogenous Metabolites Exogenous Constituents Blood Absorption TCM Studies Drug Toxicology Health Management Sports Food Cyperi Rhizoma Extract Cyperi Rhizoma Processed With Vinegar (CRV) Sprague Dawley Rats
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