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Journal / Immunology and Infection / Genredigering av primära Rhesus Macaque B-celler
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Genredigering av primära Rhesus Macaque B-celler
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Genredigering av primära Rhesus Macaque B-celler

Article DOI: 10.3791/64858-v • 09:53 min • February 10th, 2023
February 10th, 2023 •
1, 2, 2, 3,5, 1, 1,6, 1, 2, 1,4
1Laboratory of Molecular Immunology, The Rockefeller University, 2Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 3Laboratory of Retrovirology, The Rockefeller University, 4Howard Hughes Medical Institute, The Rockefeller University, 5Laboratory of Applied Virology and Precision Medicine, King Abdullah University of Science and Technology (KAUST), 6Vaccine and Immunotherapy Center, Wistar Institute

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Vi presenterar en metod för odling och genredigering av primära rhesusmakak B-celler med CRISPR/Cas9 och rekombinant adenoassocierat virus serotyp 6 för studier av B-cellsterapier.

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Denna månad i JoVE nummer 192 B-celler genredigering genomteknik CRISPR / Cas9 adenoassocierat virus rhesusmakak icke-mänsklig primat cellterapi
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