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Medicine

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A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
 

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

Article DOI: 10.3791/64914-v 05:18 min February 17th, 2023
February 17th, 2023

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Summary

The streptozotocin-induced diabetic wound model in male SD rats is currently the most widely used model for studying wound healing in type I diabetes mellitus. This protocol describes the methods used to construct this model. It also presents and addresses potential challenges and examines the progression and angiogenic characteristics of diabetic wounds.

Tags

Rat Wound Model Type 1 Diabetes Protocol Chronic Diabetic Wounds Streptozotocin Solution Wound Creation Sodium Citrate Buffer Intraperitoneal Injection Blood Glucose Levels
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