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Gross and Fine Dissection of Inner Ear Sensory Epithelia in Adult Zebrafish (Danio rerio)
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Gross and Fine Dissection of Inner Ear Sensory Epithelia in Adult Zebrafish (Danio rerio)

Article DOI: 10.3791/1211-v • 08:03 min • May 8th, 2009
May 8th, 2009 •
1,2, 1
1Genome Technology Branch, National Human Genome Research Institute, 2Neuroscience and Cognitive Science Program, University of Maryland

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The inner ear sensory epithelium of adult zebrafish is a good model system for understanding the mechanisms of hair cell regeneration in adult vertebrates. This protocol demonstrates the fine dissection of the epithelia, through which we can get tissue samples for studying the regenerative events at cellular and subcellular levels.

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Inner Ear Sensory Epithelia Gross Dissection Fine Dissection Zebrafish Hair Cells Supporting Cells Cellular Features Molecular Features Inner Ear HC Regeneration Clinical Therapy Hearing/balance Deficits Tissue Sections Detailed Structure Heterogeneity Whole-mount Epithelial Samples
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