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Dwars Aorta Vernauwing in Muizen
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Dwars Aorta Vernauwing in Muizen

Article DOI: 10.3791/1729-v • 08:25 min • April 21st, 2010
April 21st, 2010 •
1, 1, 1,2
1Department of Molecular Physiology and Biophysics, Baylor College of Medicine (BCM), 2The Margaret M. and Albert B. Alkek Department of Medicine, Baylor College of Medicine (BCM)

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Dwars aorta vernauwing (TAC) in de muis is een veel gebruikte experimenteel model om de mechanismen die ten grondslag liggen cardiale hypertrofie en hartfalen ontwikkeling te bestuderen. Hier beschrijven we de procedures aan vernauwen de aorta naar een reproduceerbare mate van cardiale hypertrofie in muizen te creëren.

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Geneeskunde Aorta hartfalen hypertrofie muis druk-overbelasting
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