Christopher Hughes: An in vitro model for the Study of Angiogenesis (Interview)

Biology

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Summary

Christopher C.W. Hughes describes the utility of his culture system for studying angiogenesis in vitro. He explains the importance of fibroblasts that secrete a critical, yet unidentified, soluble factor that allow endothelial cells to form vessels in culture that branch, form proper lumens, and undergo anastamosis.

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Hughes, C. C. Christopher Hughes: An in vitro model for the Study of Angiogenesis (Interview). J. Vis. Exp. (3), e175, doi:10.3791/175 (2007).

Abstract

Christopher C.W. Hughes describes the utility of his culture system for studying angiogenesis in vitro. He explains the importance of fibroblasts that secrete a critical, yet unidentified, soluble factor that allow endothelial cells to form vessels in culture that branch, form proper lumens, and undergo anastamosis.

Disclosures

The authors have nothing to disclose.

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