Ole Isacson: développement de nouvelles thérapies pour la maladie de Parkinson

Biology

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Summary

Ole Isacson donne un aperçu concis de la maladie de Parkinson est, ses causes, les stratégies thérapeutiques et les progrès de la recherche sur le Parkinson.

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Isacson, O. Ole Isacson: Development of New Therapies for Parkinson's Disease. J. Vis. Exp. (3), e189, doi:10.3791/189 (2007).

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Abstract

References

  1. Chung, C. Y., Seo, H., Sonntag, K. C., Brooks, A., Lin, L., Iasacson, O. Cell type specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability. Hum. Mol. Genet. 14, 1709-1725 (2005).
  2. Mendez, I., Sanchez-Pernaute, R., Cooper, O., Vinuela, A., Ferrari, D., Bjoerklund, L., Dagher, A., Isacson, O. Cell type analysis of fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease. Brain. 128, (7), 1498-1510 (2005).
  3. Cooper, O., Isacson, O. Intrastiatal Transforming Growth Factor Delivery to a Model of Parkinson's Disease Induces Proliferation and Migration of Endogenous Adult Neural Progenitor Cells without Differentiation into Dopaminergic Neurons. J. Neurosci. 24, (41), 8924-8931 (2004).
  4. Sanchez-Pernaute, R., Ferree, A., Cooper, O., Yu, M., Brownell, A. L., Isacson, O. Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat mod of Parkinson's disease. Journal of Neuroinflammation. (2004).
  5. Isacson, O. The production and use of cells as therapeutic agents in neurodegenerative diseases. Lancet Neurology. 2, (7), 417-424 (2003).

Comments

5 Comments

  1. nice

    Reply
    Posted by: Anonymous
    July 22, 2009 - 3:13 AM
  2. i know you want to see my comment "very interesting" so here it is : very interesting

    Reply
    Posted by: Anonymous
    October 14, 2009 - 5:04 PM

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