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Journal / Neuroscience / 脑室周围白质软化的小鼠模型
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Neuroscience

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JoVE Journal Neuroscience
脑室周围白质软化的小鼠模型
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脑室周围白质软化的小鼠模型

Article DOI: 10.3791/1951-v • 06:24 min • May 18th, 2010
May 18th, 2010 •
1, 1, 1
1Department of Cell Biology and Human Anatomy Institute for Pediatric Regenerative Medicine School of, University of California, Davis

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我们建立了脑室周围白质软化（PVL），早产儿脑室周围脑白质病变​​为特征的主导性脑损伤的小鼠模型。 / /没有全身性感染的缺氧缺血PVL的主要原因。单侧颈动脉结扎和缺氧暴露/无脂多糖注射创建在P6小鼠PVL的样病变。

Tags

朱庇特，第39期神经科学，脑，鼠标，脑白质损伤，少突胶质细胞，脑室周围白质软化
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