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PAR-Clip - En metod för att identifiera transkriptom hela bindningar på RNA-proteiner
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PAR-Clip - En metod för att identifiera transkriptom hela bindningar på RNA-proteiner

Article DOI: 10.3791/2034-v • 12:24 min • July 2nd, 2010
July 2nd, 2010 •
1, 2, 3, 3, 4, 4, 1, 1, 2, 2, 1, 1, 5, 3, 1
1Howard Hughes Medical Institute, Laboratory of RNA Molecular Biology, Rockefeller University, 2Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine, 3Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB), 4Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB), 5Genomics Resource Center, Rockefeller University

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RNA-transkript är föremål för omfattande posttranscriptional reglering som förmedlas av en mängd gränsöverskridande agerar RNA-bindande proteiner (RBPs). Här presenterar vi en generaliserbar metod för att identifiera exakt och på ett transkriptom-omfattande RNA-bindning med RBPs.

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Cellbiologi UV crosslinking RNA bindande proteiner RNA-bindande motiv 4-thiouridine 6-thioguanosine
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