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Immunology and Infection

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JoVE Journal Immunology and Infection
Bewertung von immunologisch relevanten dynamischen tertiären strukturellen Merkmale der HIV-1 V3-Loop Crown R2 Sequence durch Ab initio Folding
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Bewertung von immunologisch relevanten dynamischen tertiären strukturellen Merkmale der HIV-1 V3-Loop Crown R2 Sequence durch Ab initio Folding

Article DOI: 10.3791/2118-v • 10:51 min • September 15th, 2010
September 15th, 2010 •
1, 1
1Department of Pharmacology, School of Medicine, New York University

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Die Krone Region unterschiedliche V3-Loop-Sequenzen von der Oberfläche Hüllglycoprotein (gp120) des HIV-1 kann strukturell in vielen Fällen gekennzeichnet durch in silico Faltung von Positionen 10 bis 22 der Schleife mit einer state-of-the-art

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Infektion HIV-1 Struktur-Aktivitäts-Beziehungen ab initio Simulationen Antikörper-vermittelten Neutralisation Impfstoff-Design
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