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Optic Nerve transsectie
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Optic Nerve transsectie: Een model van de volwassen Neuron Apoptosis in het centrale zenuwstelsel

Article DOI: 10.3791/2241-v • 12:06 min • May 12th, 2011
May 12th, 2011 •
*1, *1, 1
1Department of Surgery, University of Toronto
* These authors contributed equally

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Optic Nerve doorsnijding is een veel gebruikt model van de volwassen CNS verwonding. Negentig procent van de retinale ganglioncellen (RGC), waarvan de axonen volledig doorsneden (axotomy) sterven binnen 14 dagen na axotomy. Dit model is lastig om experimentele manipulaties en zeer reproduceerbaar.

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Neurowetenschappen nummer 51 het centraal zenuwstelsel Retina Apoptosis retinale ganglion cel axotomy Optic Nerve transsectie Rat Retrograde Labeling Rat Model
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