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JoVE Journal Neuroscience
Synnerven transection
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Synnerven transection: En modell av Vuxen Neuron apoptos i det centrala nervsystemet

Article DOI: 10.3791/2241-v • 12:06 min • May 12th, 2011
May 12th, 2011 •
*1, *1, 1
1Department of Surgery, University of Toronto
* These authors contributed equally

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Synnerven transection är en allmänt använd modell av vuxna CNS-skada. Nittio procent av retinal ganglion celler (RGC: er), vars axoner är helt transected (axotomy) dör inom 14 dagar efter axotomy. Denna modell är lätta att experimentella manipulationer och mycket reproducerbar.

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Neurovetenskap 51 frågan centrala nervsystemet Retina apoptos retinal Ganglion Cell Axotomy Optic Nerve transection Råtta Retrograd märkning Rat modell
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