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iCLIP - Bireysel Nükleotid Çözünürlük protein-RNA Etkileşimleri Transcriptome geniş Haritalama
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iCLIP - Bireysel Nükleotid Çözünürlük protein-RNA Etkileşimleri Transcriptome geniş Haritalama

Article DOI: 10.3791/2638-v • 10:45 min • April 30th, 2011
April 30th, 2011 •
1, 2, 3, 3, 1, 3, 4, 2, 1
1Laboratory of Molecular Biology, Medical Research Council - MRC, 2European Bioinformatics Institute, EMBL Heidelberg, 3Computer and Information Science, University of Ljubljana, 4Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute

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Transkript RNA bağlayıcı proteinlerin mekansal düzenleme, post-transkripsiyonel regülasyonunda önemli bir belirleyicisidir. Bu nedenle, bir RNA bağlayıcı protein bağlama bölgeleri hassas genom haritalama sağlar bireysel nükleotid çözünürlük UV crosslinking ve immunoprecipitation (iCLIP) geliştirdi.

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Hücresel Biyoloji Sayı 50 RNA biyokimya transcriptome sistem biyolojisi RNA bağlayıcı protein
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