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Journal / Immunology and Infection / Induktion av Alloantigen-specifika anergi på…
JoVE Journal
Immunology and Infection

This content is Open Access.

JoVE Journal Immunology and Infection
Induktion av Alloantigen-specifika anergi på humana perifera mononukleära blodceller genom Alloantigen stimulering med Co-stimulerande signal Blockade
A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Journal (Immunology and Infection)
A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Examination of the Telomere G-overhang Structure in Trypanosoma brucei
Journal (Immunology and Infection)
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Induktion av Alloantigen-specifika anergi på humana perifera mononukleära blodceller genom Alloantigen stimulering med Co-stimulerande signal Blockade

Article DOI: 10.3791/2673-v • 11:55 min • March 14th, 2011
March 14th, 2011 •
1,2, 1, 1, 1,2, 3,4
1Medical Oncology, Dana Farber Cancer Institute, 2Department of Medicine, Brigham and Womens Hospital, 3Pediatric Oncology, Dana Farber Cancer Institute, 4Division of Hematology/Oncology, Children’s Hospital Boston

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Click here for the English version.

Detta dokument beskriver en enkel teknik för att inducera alloantigen-specifika anergi i humana perifera mononukleära blodceller. Tekniken kan användas kliniskt för att generera icke-alloreactive donator celler. Infusion av dessa celler skulle kunna förbättra immunförsvaret beredning och minska toxicitet efter allogen hematopoetisk stamcellstransplantation.

Tags

Immunologi 49 allogen stamcellstransplantation alloreactivity Graft-versus-Host Disease T-cell costimulation anergi blandad lymfocyter reaktion.
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