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Bioengineering

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JoVE Journal Bioengineering
Eine Methode zur Ovarialfollikel Encapsulation und Kultur in einem Proteolytisch Degradable 3 Dimensional-System
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Eine Methode zur Ovarialfollikel Encapsulation und Kultur in einem Proteolytisch Degradable 3 Dimensional-System

Article DOI: 10.3791/2695-v • 12:37 min • March 15th, 2011
March 15th, 2011 •
1, 2, 2,3,4, 1,4,5
1Institute for BioNanotechnology in Advanced Medicine, Northwestern University, 2Department of Obstetrics and Gynecology, Northwestern University, Feinberg School of Medicine, 3Center for Reproductive Research, Northwestern University, 4The Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 5Department of Chemical and Biological Engineering, Northwestern University

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Eine neue Methode zur Ovarialfollikel Kapselung in einer 3D-Fibrin-Alginat durchdringendes Netzwerk beschrieben. Dieses System kombiniert strukturelle Unterstützung mit proteolytischen Abbau der Entwicklung von unreifen Follikeln Unterstützung, um zu reifen Eizellen zu produzieren. Diese Methode kann zur Kultur Zellaggregate angewendet werden, um Zell-Zell-Kontakte ohne Beschränkungen für die Ausweitung aufrecht zu erhalten.

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Bioengineering Ovarialfollikel Fibrin-Alginat 3D-Kultur-System dynamischen Umfeld
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