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JoVE Journal
Medicine

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Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
 
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Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Article DOI: 10.3791/3107-v 11:24 min October 18th, 2011
October 18th, 2011

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Summary

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Click here for the English version.

Brain tumor patients routinely undergo cranial radiotherapy, and while beneficial, this treatment often results in debilitating cognitive dysfunction. This serious unresolved problem has at present, no clinical recourse, and has driven our efforts to devise stem cell based therapies for the recovery of radiation-induced cognitive decrements.

Tags

Stem Cell Transplantation Cognitive Dysfunction Cranial Radiotherapy Brain Tumors Neural Stem Cells Radiation-induced Cognitive Decline Athymic Nude Rats Hippocampus Human Neural Stem Cells (hNSCs) Cognition Improvement Grafted Cell Survival Differentiation-specific Markers
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