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JoVE Journal
Bioengineering

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Lensless Fluorescent Microscopy on a Chip
 
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Lensless Fluorescent Microscopy on a Chip

Article DOI: 10.3791/3181-v 11:23 min August 17th, 2011
August 17th, 2011

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Summary

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Click here for the English version.

A lensless on-chip fluorescent microscopy platform is demonstrated that can image fluorescent objects over an ultra-wide field-of-view of e.g., >0.6-8 cm2 with <4μm resolution using a compressive sampling based decoding algorithm. Such a compact and wide-field fluorescent on-chip imaging modality could be valuable for high-throughput cytometry, rare-cell research and microarray-analysis.

Tags

Lensless Fluorescent Microscopy On-chip Imaging High-throughput Screening Compact Designs Digital Reconstruction Algorithms Spatial Resolution Field-of-view (FOV) Fluorescent Excitation Total-internal-reflection (TIR) Micro-fluidic Chip Fiber-optic Faceplate Optoelectronic Sensor Array Charge-coupled-device (CCD) Compressive-sampling Based Decoding Algorithm Micro-channels
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